Colorectal Cancer Therapeutics in Asia-Pacific Markets to 2024-Launch of Premium Targeted Therapies and Increasing Prevalence to Drive the Market

Colorectal Cancer (CRC) is the most common cancer and the leading cause of cancer-related mortality globally. The five-year prevalence population for CRC in Asia-Pacific was 1.7 million in 2017. This figure has been gradually rising with the growing elderly population and increasingly Westernized lifestyles.

CRC is a leading cause of death worldwide, accounting for 0.77 million deaths in 2015. Over half of the incident cases of CRC are diagnosed in patients over the age of 50, and as the aged population is projected to grow, the prevalence of CRC is anticipated to increase, acting as a driver for revenue growth. The poor prognosis, particularly for patients with advanced disease, has created a pressing need for improved therapeutic options.

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The CRC market is therefore shifting from a focus on generic chemotherapy regimens to a complex treatment landscape based on the presence of various molecular aberrations. The marketed products landscape comprises a wide range of treatment options, including EGFR-targeted therapies, angiogenesis inhibitors, multiple kinase inhibitors and new chemotherapies.

In the current market, RAS-wild-type and RAS-mutant patients can be treated with angiogenesis inhibitors such as Avastin, Cyramza and Zaltrap, while patients with RAS-or KRAS-wild-type mutations can be prescribed EGFR-targeted therapies such as Erbitux and Vectibix. However, significant unmet need remains for products that can treat BRAF-mutant CRC patients.

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Table of Contents:

1 Table of Contents 5

2 Introduction 10

3 Marketed Products 27

4 Pipeline Analysis 44

5 Clinical Trial Analysis 64

6 Multi-scenario Forecast 75

7 Drivers and Barriers 92

8 Deals and Strategic Consolidations 96

9 Appendix 110

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Posted by on Monday May 20 2019, 6:45 AM EDT. All trademarks acknowledged. Filed under Business & Financial Services, Business Services, Diagnostics, Featured Press Release, Healthcare, Life Sciences, Pharmaceuticals. Comments and Trackbacks closed. Follow responses: RSS 2.0

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